| 中文名 | (betaR)-beta-环戊基-4-(7H-吡咯并[2,3-d]嘧啶-4-基)-1H-吡唑-1-丙腈
|
| 英文名 | Ruxolitinib
|
| 别名 | 鲁索替尼
芦可替尼
卢索替尼
鲁索利替尼
鲁索利替尼杂质
酪氨酸蛋白激酶抑制剂
JAK1和JAK2抑制剂(RUXOLITINIB)
Β-环戊基-4-(7H-吡咯并[2,3-D]嘧啶-4-基)-(ΒR)-1H-吡唑-1-丙腈
(betaR)-beta-环戊基-4-(7H-吡咯并[2,3-d]嘧啶-4-基)-1H-吡唑-1-丙腈
(BETAR)-BETA-环戊基-4-(7H-吡咯并[2,3-D]嘧啶-4-基)-1H-吡唑-1-丙腈
|
| 英文别名 | Jakafi
INCB 018424
Ruxolitinib
Roxolitinib
incb-018424
INCB018424 (Ruxolitinib)
Ruxolitinib (INCB 018424)
β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-(βR)-1H-pyrazole-1-propanenitrile
(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}-1H-pyrazol-1-yl)propanenitrile
(3R)-3-(4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
(betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
(betar)-beta-cyclopentyl-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazole-1-propanenitrile
|
| CAS | 941678-49-5
1092939-17-7
|
| EINECS | 1312995-182-4 |
| 化学式 | C17H18N6
|
| 分子量 | 306.37 |
| 密度 | 1.40 |
| 熔点 | 84-89°C |
| 溶解度 | Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming). |
| 酸度系数 | 11.63±0.50(Predicted) |
| 存储条件 | -20° |
| 稳定性 | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| 外观 | White powder. |
| 颜色 | White |
