中文名 | 醋酸去氨加压素 |
英文名 | Desmopressin Acetate |
别名 | 醋酸去氨加压素 去氨基精加压素 LKT去氨加压素 1-去氨基-8-右旋精氨酸加压素 醋酸去氨加压素 16789-98-3 DESMOPRESSIN ACETATE 去氨加压素 醋酸去氨加压素 DESMOPRESSINACETATE [去氨基-CYS1, D-ARG8]-加压素 乙酸盐 水合物 |
英文别名 | ddavp DDAVP DESMORESSIN ACETATE DesmopressinAcetate Desmopressin Acetate DESMOPRESSIN ACETATE DESMOPRESSIN MONOACETATE DESMOPRESSIN ACETATE SALT 1-Deamino-8-D-arginine-vasopressin diacetate 1-deamino-8-d-arginine-vasopressin diacetate 1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin diacetate 1-(3-mercaptopropionic acid)-8-d-arginine-vasopressin diacetate |
CAS | 16789-98-3 |
EINECS | 634-101-1 |
化学式 | C48H68N14O14S2 |
分子量 | 1129.28 |
InChI | InChI=1/C46H64N14O12S2.2C2H4O2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25;2*1-2(3)4/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52);2*1H3,(H,3,4) |
熔点 | 170-172°C (dec.) |
溶解度 | Acetic Acid (Slightly), Methanol (Slightly), Water (Slightly) |
存储条件 | ?20°C |
外观 | Solid |
颜色 | White to Off-White |
物化性质 | 近年新合成的加压素类物质,即将精加压素的1位半胱氨酸和8位L-精氨酸分别换成β-巯基丙酸和D-精氨酸。本品加压作用比精加压素小2000倍,而抗利尿作用比天然加压素强且持久,半衰期长3倍。 |